[HTML][HTML] Design and synthesis of new 4-(3, 4, 5-trimethoxyphenyl) thiazole–pyrimidine derivatives as potential antiproliferative agents
… 3,4,5-trimethoxyphenyl thiazole pyrimidines has been synthesized and biologically evaluated
… of anticancer agents and generate new TMP thiazole derivatives with good anticipated …
… of anticancer agents and generate new TMP thiazole derivatives with good anticipated …
2, 4, 5-trisubstituted thiazole: A privileged scaffold in drug design and activity improvement
Z Zhang, B Shu, Y Zhang, GS Deora… - Current Topics in …, 2020 - ingentaconnect.com
… Among them, tubulin has now become an attractive target for anti-tumor drugs [59]. In …
of the thiazole ring and gained the 2-substituted-4(3’,4’,5’-trimethoxy-phenyl)-5-aryl thiazole …
of the thiazole ring and gained the 2-substituted-4(3’,4’,5’-trimethoxy-phenyl)-5-aryl thiazole …
Synthesis of new thiazole derivatives and evaluation of their antimicrobial and cytotoxic activities
… having a 2,4-disubstituted thiazole ring were reported to have anticancer activity as well as
… [ Citation 36–42 ] Clinically available thiazole-containing anticancer drugs act as inosine 5′-…
… [ Citation 36–42 ] Clinically available thiazole-containing anticancer drugs act as inosine 5′-…
Synthesis and biological evaluation of small anticancer molecules acting as tubulin polymerization inhibitors
P Oliva - 2020 - sfera.unife.it
… Over 60% of chemotherapeutic agents currently used in … Here we describe replacing the
thiazole nucleus with the less … the 3’,4’,5’trimethoxyphenyl moiety, identical to the A-ring of CA-…
thiazole nucleus with the less … the 3’,4’,5’trimethoxyphenyl moiety, identical to the A-ring of CA-…
Synthesis of thiazole linked chalcones and their pyrimidine analogues as anticancer agents
C Kesari, KR Rama, K Sedighi, J Stenvang… - Synthetic …, 2021 - Taylor & Francis
… In summary, we synthesized and evaluated a novel series of thiazole linked chalcone analogs
as anticancer agents. Many of these thiazole analogs showed significant antiproliferative …
as anticancer agents. Many of these thiazole analogs showed significant antiproliferative …
[HTML][HTML] Synthesis, modeling, and biological studies of new thiazole-pyrazole analogues as anticancer agents
GRS Ashour, AF Qarah, AF Alrefaei, AI Alalawy… - Journal of Saudi …, 2023 - Elsevier
… , we have been fascinated to synthesize new thiazole-pyrazole hybrids (Fig. 2) incorporating
an amide linker to act as potent anticancer agents and investigate their structural-electronic …
an amide linker to act as potent anticancer agents and investigate their structural-electronic …
Thiazole-containing compounds as therapeutic targets for cancer therapy
… of some clinically applied anticancer drugs, such as dasatinib, … 2-substituted-4-(3ʹ,4ʹ,5ʹ-trimethoxyphenyl)-5-aryl
thiazole-… ) with 3,4,5-trimethoxyphenyl group at the C-4 position and 4-…
thiazole-… ) with 3,4,5-trimethoxyphenyl group at the C-4 position and 4-…
Synthesis and molecular docking study of new thiazole derivatives as potential tubulin polymerization inhibitors
… novel antitumor agents, we are particularly interested in the present work with thiazoles as …
directed to gather two bioactive entities (3,4,5-trimethoxyphenyl and 2-aminothiazole) into one …
directed to gather two bioactive entities (3,4,5-trimethoxyphenyl and 2-aminothiazole) into one …
[PDF][PDF] synthesis and Biological evaluation of 2-Methyl-4, 5-Disubstituted oxazoles as a Novel Class of Highly Potent Antitubulin Agents
… Here we describe replacing the thiazole nucleus with the … Synthesis and biological evaluation
of 2-substituted-4-(3′ ,4′ ,5′ -trimethoxyphenyl)-5-aryl thiazoles as anticancer agents…
of 2-substituted-4-(3′ ,4′ ,5′ -trimethoxyphenyl)-5-aryl thiazoles as anticancer agents…
[HTML][HTML] Development and therapeutic potential of 2-aminothiazole derivatives in anticancer drug discovery
SR Alizadeh, SM Hashemi - Medicinal Chemistry Research, 2021 - Springer
… to develop potent and selective anti-tumor drugs, a number of novel 2-amino-thiazole-5- …
were designed and synthesized by Liu et al. According to biological evaluation results, …
were designed and synthesized by Liu et al. According to biological evaluation results, …